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Title Immunosuppressive effects of metrifonate on oreochromis niloticus التأثيرات المثبطة للمناعة للميتروفونات على البلطى النيلى
Full text http://hdl.handle.net/1834/1218
Date 2005
Author(s) El-Gohary, M.S.; Mohamed, S.G.; Khalil, R.H.; El-Banna, S.; Soliman, M.K.
Abstract This journal is published by NIOF, Alexandria, Egypt - The effect of metrifonate on the immunity of the exposed fish are evaluated through the determination of the antibody titer and mortality rate during the challenge trial. In the chronic toxic exposure to metrifonate by dose 0.17mg/liter for 8 weeks, the more clear signs were darkness of fish color with hemorrhagic patches & loosing of scale at end of the trial the color return to normal. Determination of some blood parameters revealed significant decrease of white blood cell count, as there were lymphopenia and nueutrophilia during the chronic exposure to metrifonate. Phagocytic assay revealed a significant decrease in both phagocytic activity (PA) and phagocytic index(PI).Hypoproteinami hypoglobulinaemia and hypoalbuminaemia were observed. The challenge trial indicted that, the metrifonate decrease the immunity of exposed fish.. The using of biogen"R" as a growth promoter in fish diet minimized the toxicity of metrifonate. - NIOF
Subject(s) Immunosuppressive, Metrifonate, Oreochromis niloticus; BIOLOGY
Language en
Publisher Alexandria: National Institute of Oceanography and Fisheries
Type of publication Article
Format 53690 bytes; 128656 bytes; application/pdf; application/pdf
Identifier Egyptian Journal of Aquatic Research, 31 (1), p. 448 - 458; 1110-0354
Repository Africa - Ocean Data and Information Network of Africa (OdinAfrica)
Added to C-A: 2008-12-22;01:53:18