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Title The role of human breast milk mucus and mucins in HIV-AIDS
Full text http://hdl.handle.net/11427/11999
Date 2012
Author(s) Mthembu, Yolanda
Contributor(s) Mall, Anwar Suleman
Abstract Includes abstract. - Includes bibliographical references. - Milk molecules such as mucins, antibodies, bactericidal enzymes like lysozymes and fatty acids that lyse bacteria, viral particles and bacterial peptides, offer anti-microbial activity in milk. Despite human breast milk being rich in anti-microbial substances, such as mucin, that protect against pathogens and viruses, it remains a significant route of HIV transmission from mother to child. ... The objectives of the study were to isolate, purify, identify and investigate the anti-HIV-1 activity of crude breast milk particularly the human milk fat globule material (MFGM) and its purified mucin components, in HIV positive patients (n = 20) compared with those who are not infected (n = 20). This study also tested the effect that heat (80°C, 10 min) might have on breast milk which might release the milk mucins and consequently have an inhibitory effect on HIV-1.
Subject(s) Medical Science
Language eng
Publisher University of Cape Town; Department of Surgery
Type of publication Masters; MSc
Repository Cape Town - OpenUCT, University of Cape Town
Added to C-A: 2017-02-17;13:37:57